Serotonin Regulates Rhythmic Whisking
نویسندگان
چکیده
منابع مشابه
Serotonin Regulates Rhythmic Whisking
Many rodents explore their environment by rhythmically palpating objects with their mystacial whiskers. These rhythmic whisker movements ("whisking"; 5-9 Hz) are thought to be regulated by an unknown brainstem central pattern generator (CPG). We tested the hypothesis that serotonin (5-HT) inputs to whisking facial motoneurons (wFMNs) are part of this CPG. In response to exogenous serotonin, wFM...
متن کاملSerotonin and Whisking
Rhythmic whisker movements, called "whisking," are produced by a brainstem central pattern generator (CPG) that uses serotonin to induce periodic firing in facial motorneurons. During active touch, motor cortex could regulate whisking frequency by controlling the rate of firing of the serotonergic neurons.
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Whisking and sniffing are predominant aspects of exploratory behavior in rodents. We review evidence that these motor rhythms are coordinated by the respiratory patterning circuitry in the ventral medulla. A region in the intermediate reticular zone, dorsomedial to the preBötzinger inspiratory complex, provides rhythmic input to the facial motoneurons that drive protraction of the vibrissae. Ne...
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Sniffing and whisking typify the exploratory behavior of rodents. These actions involve separate oscillators in the medulla, located respectively in the pre-Bötzinger complex (preBötC) and the vibrissa-related region of the intermediate reticular formation (vIRt). We examine how these oscillators synergize to control sniffing and whisking. We find that the vIRt contains glycinergic/GABAergic ce...
متن کاملAnticipatory activity of motor cortex in relation to rhythmic whisking.
Rats characteristically generate stereotyped exploratory (5-12 Hz) whisker movements, which can also be adaptively modulated. Here we tested the hypothesis that the vibrissal representation in motor cortex (vMCx) initiates and modulates whisking by acting on a subcortical whisking central pattern generator (CPG). We recorded local field potentials (LFPs) in vMCx of behaving Sprague-Dawley rats ...
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ژورنال
عنوان ژورنال: Neuron
سال: 2003
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(03)00391-x